戻し交配および戻し交配後の兄妹交配バックグラウンド系統:C57BL/6JJcl Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> Natl. Inst. Humanities C(3〜6か月) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Hum. Mol. Genet., 8, 1589-1598 (1999). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Toshikuni Sasaoka is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. BSG-KO (C57BL/6J), B6-Sgcb KO BSG-KO (C57BL/6J), B6-Sgcb KO true 笹岡 俊邦 Heterozygote x Wild-type [C57BL/6JJcl] Developed by Toshikuni Sasaoka, National Institutes of Natural Sciences (National Institute of Neuroscience, National Center of Neurology and Psychiatry). RBRC02268 C (3-6 months) B6.129S4-Sgcb<tm1Oza> B6.129S4-Sgcb<tm1Oza> 戻し交配および戻し交配後の兄妹交配 バックグラウンド系統:C57BL/6JJcl 大学共同利用機関法人 自然科学研究機構 条件を付加する。<br>研究成果の公表にあたって寄託者の指定する文献を引用する。Hum. Mol. Genet., 8, 1589-1598 (1999). <br>利用者は、研究成果の公表にあたって、笹岡俊邦博士へ謝辞の表明を必要とする。利用者が本件リソースを使用して得られた研究成果に基づき特許等の申請、及び事業活動を行う場合は、寄託者と別途協議を行う。 Toshikuni SASAOKA Beta-sarcoglycan (Sgcb) gene knockout mice. Sgcb is an integral component of the dystrophin-glycoprotein complex. Homozygous mutant mice show progressive muscular dystrophy with extensive degeneration and regeneration. β-sarcoglycan (Sgcb) 遺伝子のノックアウトマウス。 <a href='https://brc.riken.jp/mus/pcr02268'>Genotyping protocol -PCR-</a> E coli neo, mouse beta-sarcoglycan (BSG) genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter) 基礎生物学研究所(国立精神・神経医療研究センター神経研究所)・笹岡俊邦。